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Novel splice variants of cyclin E with altered substrate specificity

Cyclin E, a G(1) cyclin, is overexpressed and present in low molecular weight (LMW) isoforms in breast cancer cells and tumor tissues. In this study we have examined the possibility that the shortened mRNA splice variants could give rise to tumor-specific cyclin E LMW proteins. We used the Splice Ca...

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Detalhes bibliográficos
Main Authors: Porter, Donald C., Keyomarsi, Khandan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115185/
https://ncbi.nlm.nih.gov/pubmed/11095697
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