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Interstitial telomere sequences disrupt break-induced replication and drive formation of ectopic telomeres
Break-induced replication (BIR) is a mechanism used to heal one-ended DNA double-strand breaks, such as those formed at collapsed replication forks or eroded telomeres. Instead of utilizing a canonical replication fork, BIR is driven by a migrating D-loop and is associated with a high frequency of m...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736798/ https://ncbi.nlm.nih.gov/pubmed/33264397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1081 |
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