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Metal-free nucleophilic trifluoromethylselenolation via an iodide-mediated umpolung reactivity of trifluoromethylselenotoluenesulfonate

We report herein a practical method to generate CF(3)Se(−) (and R(F)Se(−)) anions from shelf-stable reagents under iodide activation. Metal-free nucleophilic trifluoromethylselenolations have been then performed with this in situ-generated anion. Perfluoroalkylselenolations have also been described....

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Veröffentlicht in:Beilstein J Org Chem
Hauptverfasser: Grollier, Kevin, Taponard, Alexis, De Zordo-Banliat, Arnaud, Magnier, Emmanuel, Billard, Thierry
Format: Artigo
Sprache:Inglês
Veröffentlicht: Beilstein-Institut 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736694/
https://ncbi.nlm.nih.gov/pubmed/33363671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.252
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