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Differential effects of integrase strand transfer inhibitors, elvitegravir and raltegravir, on oligodendrocyte maturation: a role for the integrated stress response

Regardless of adherence to combined antiretroviral therapy, white matter and myelin pathologies persist in patients with HIV-associated neurocognitive disorders, a spectrum of cognitive, motor, and behavioral impairments. We hypothesized that antiretroviral therapy alters the maturation of oligodend...

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Publicat a:Glia
Autors principals: Roth, Lindsay M., Zidane, Bassam, Festa, Lindsay, Putatunda, Raj, Romer, Micah, Monnerie, Hubert, Jordan-Sciutto, Kelly L., Grinspan, Judith B.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736549/
https://ncbi.nlm.nih.gov/pubmed/32894619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23902
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