Antigen Specificity Enhances Disease Control by Tregs in Vitiligo

Vitiligo is an autoimmune skin disease characterized by melanocyte destruction. Regulatory T cells (Tregs) are greatly reduced in vitiligo skin, and replenishing peripheral skin Tregs can provide protection against depigmentation. Ganglioside D3 (GD3) is overexpressed by perilesional epidermal cells...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Mukhatayev, Zhussipbek, Dellacecca, Emilia R., Cosgrove, Cormac, Shivde, Rohan, Jaishankar, Dinesh, Pontarolo-Maag, Katherine, Eby, Jonathan M., Henning, Steven W., Ostapchuk, Yekaterina O., Cedercreutz, Kettil, Issanov, Alpamys, Mehrotra, Shikhar, Overbeck, Andreas, Junghans, Richard P., Leventhal, Joseph R., Le Poole, I. Caroline
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736409/
https://ncbi.nlm.nih.gov/pubmed/33335528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.581433
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