A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo

T cell cytolytic activity targeting epidermal melanocyte is shown to cause progressive depigmentation and autoimmune vitiligo. Using the recently developed transgenic mice h3TA2 that carry T cell with a HLA-A2 restricted human tyrosinase reactive TCR and develop spontaneous vitiligo from an early ag...

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Autori principali: Chatterjee, Shilpak, Eby, Jonathan, Al-Khami, Amir A., Soloshchenko, Myroslawa, Kang, Hee-Kap, Kaur, Navtej, Naga, Osama, Murali, Anuradha, Nishimura, Michael I., Le Poole, I. Caroline, Mehrotra, Shikhar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989443/
https://ncbi.nlm.nih.gov/pubmed/24366614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.540
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