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A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo
T cell cytolytic activity targeting epidermal melanocyte is shown to cause progressive depigmentation and autoimmune vitiligo. Using the recently developed transgenic mice h3TA2 that carry T cell with a HLA-A2 restricted human tyrosinase reactive TCR and develop spontaneous vitiligo from an early ag...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989443/ https://ncbi.nlm.nih.gov/pubmed/24366614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.540 |
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