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A modular template for the design of thiol-triggered sensors and prodrugs
A unique reaction between thiols (RSH) and alkyl sulfonylbenzothiazole was discovered. This reaction was specific for thiols and produced a sulfinic acid (RSO(2)H) as the intermediate, which further triggered an intramolecular cyclization to release a -OH containing payload. This reaction was used t...
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| Yayımlandı: | Spectrochim Acta A Mol Biomol Spectrosc |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736145/ https://ncbi.nlm.nih.gov/pubmed/33128946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.saa.2020.119072 |
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