A Four Week Trial of Hypertonic Saline in Children with Mild Cystic Fibrosis Lung Disease: Effect on Mucociliary Clearance and Clinical Outcomes

BACKGROUND: Hypertonic saline (HS) is commonly prescribed for children with cystic fibrosis (CF) despite the absence of strong data indicating clinical efficacy in a population with mild lung disease. We hypothesized that HS treatment would result in a sustained improvement in mucociliary clearance...

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Pubblicato in:J Cyst Fibros
Autori principali: Donaldson, Scott H., Samulski, T. Danielle, LaFave, Caroline, Zeman, Kirby, Wu, Jihong, Trimble, Aaron, Ceppe, Agathe, Bennett, William D., Davis, Stephanie D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736104/
https://ncbi.nlm.nih.gov/pubmed/32669217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2020.07.009
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