Duration of action of hypertonic saline on mucociliary clearance in the normal lung

Inhalation of hypertonic saline (HS) acutely enhances mucociliary clearance (MC) in both health and disease. In patients with cystic fibrosis (CF), repeated use of HS causes a sustained improvement in MC as well as clinical benefit. The pharmacodynamic duration of activity on MC may be an important...

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Veröffentlicht in:J Appl Physiol (1985)
Hauptverfasser: Bennett, W. D., Wu, J., Fuller, F., Balcazar, J. R., Zeman, K. L., Duckworth, H., Donn, K. H., O'Riordan, T. G., Boucher, R. C., Donaldson, S. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469922/
https://ncbi.nlm.nih.gov/pubmed/25911685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00404.2014
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