Duration of action of hypertonic saline on mucociliary clearance in the normal lung

Inhalation of hypertonic saline (HS) acutely enhances mucociliary clearance (MC) in both health and disease. In patients with cystic fibrosis (CF), repeated use of HS causes a sustained improvement in MC as well as clinical benefit. The pharmacodynamic duration of activity on MC may be an important...

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發表在:J Appl Physiol (1985)
Main Authors: Bennett, W. D., Wu, J., Fuller, F., Balcazar, J. R., Zeman, K. L., Duckworth, H., Donn, K. H., O'Riordan, T. G., Boucher, R. C., Donaldson, S. H.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469922/
https://ncbi.nlm.nih.gov/pubmed/25911685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00404.2014
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