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Effect of hypertonic saline on mucociliary clearance and clinical outcomes in chronic bronchitis

BACKGROUND: Mucus dehydration and impaired mucus clearance are common features of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). In CF, inhaled hypertonic saline (HS) improves lung function and produces sustained increases in mucociliary clearance (MCC). We hypothesised that...

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Detalhes bibliográficos
Publicado no:ERJ Open Res
Main Authors: Bennett, William D., Henderson, Ashley G., Ceppe, Agathe, Zeman, Kirby L., Wu, Jihong, Gladman, Christine, Fuller, Fred, Gazda, Stephen, Button, Brian, Boucher, Richard C., Donaldson, Scott H.
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418818/
https://ncbi.nlm.nih.gov/pubmed/32802823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00269-2020
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