Viral-induced alternative splicing of host genes promotes influenza replication

Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that infection of human lung epithelial cells with influenza A virus (IAV) also induces a broad program of alternative splicing of host genes. Although these splicing-regulated genes are...

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Publicat a:eLife
Autors principals: Thompson, Matthew G, Dittmar, Mark, Mallory, Michael J, Bhat, Prasanna, Ferretti, Max B, Fontoura, Beatriz MA, Cherry, Sara, Lynch, Kristen W
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Chromosomes and Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735754/
https://ncbi.nlm.nih.gov/pubmed/33269701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55500
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