Viral-induced alternative splicing of host genes promotes influenza replication

Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that infection of human lung epithelial cells with influenza A virus (IAV) also induces a broad program of alternative splicing of host genes. Although these splicing-regulated genes are...

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Pubblicato in:eLife
Autori principali: Thompson, Matthew G, Dittmar, Mark, Mallory, Michael J, Bhat, Prasanna, Ferretti, Max B, Fontoura, Beatriz MA, Cherry, Sara, Lynch, Kristen W
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
Soggetti:
Chromosomes and Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735754/
https://ncbi.nlm.nih.gov/pubmed/33269701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55500
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