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Galectin-9 expression defines exhausted T cells and impaired cytotoxic NK cells in patients with virus-associated solid tumors

BACKGROUND: We have previously reported that the upregulation of galectin-9 (Gal-9) on CD4(+) and CD8(+) T cells in HIV patients was associated with impaired T cell effector functions. Gal-9 is a ligand for T cell immunoglobulin and mucin domain-3, and its expression on T cells in cancer has not bee...

詳細記述

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書誌詳細
出版年:J Immunother Cancer
主要な著者: Okoye, Isobel, Xu, Lai, Motamedi, Melika, Parashar, Pallavi, Walker, John W, Elahi, Shokrollah
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735134/
https://ncbi.nlm.nih.gov/pubmed/33310773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001849
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