Cargando...

Dual-Stage Picolinic Acid-Derived Inhibitors of Toxoplasma gondii

[Image: see text] Toxoplasma gondii causes a prevalent human infection for which only the acute stage has an FDA-approved therapy. To find inhibitors of both the acute stage parasites and the persistent cyst stage that causes a chronic infection, we repurposed a compound library containing known inh...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:ACS Med Chem Lett
Main Authors: Khalifa, Muhammad M., Martorelli Di Genova, Bruno, McAlpine, Sarah G., Gallego-Lopez, Gina M., Stevenson, David M., Rozema, Soren D., Monaghan, Neil P., Morris, James C., Knoll, Laura J., Golden, Jennifer E.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734631/
https://ncbi.nlm.nih.gov/pubmed/33335660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00267
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!