Dual metabolomic profiling uncovers Toxoplasma manipulation of the host metabolome and the discovery of a novel parasite metabolic capability

The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how T. gondii manipulates host metabolism to support its overall growth rate and non-essential metabolites. To investigate this question, we measured...

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Udgivet i:PLoS Pathog
Main Authors: Olson, William J., Martorelli Di Genova, Bruno, Gallego-Lopez, Gina, Dawson, Anthony R., Stevenson, David, Amador-Noguez, Daniel, Knoll, Laura J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164669/
https://ncbi.nlm.nih.gov/pubmed/32255806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008432
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