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Dual metabolomic profiling uncovers Toxoplasma manipulation of the host metabolome and the discovery of a novel parasite metabolic capability

The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how T. gondii manipulates host metabolism to support its overall growth rate and non-essential metabolites. To investigate this question, we measured...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Olson, William J., Martorelli Di Genova, Bruno, Gallego-Lopez, Gina, Dawson, Anthony R., Stevenson, David, Amador-Noguez, Daniel, Knoll, Laura J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164669/
https://ncbi.nlm.nih.gov/pubmed/32255806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008432
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