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Expression, Purification and Characterization of a GII.4 Norovirus Protease from Minerva Virus

BACKGROUND: Noroviruses are the leading cause of acute gastroenteritis worldwide. Norovirus proteases, which are responsible for cleavage of the viral polyprotein, have become an attractive drug target to treat norovirus infections. Genogroup II (GII) noroviruses are responsible for a majority of ou...

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Detalhes bibliográficos
Publicado no:Infect Disord Drug Targets
Main Authors: Kuiper, Benjamin D., Muzzarelli, Kendall M., Keusch, Bradley J., Holcomb, Joshua, Amblard, Franck, Liu, Peng, Zhou, Shaoman, Kovari, Iulia A., Yang, Zhe, Schinazi, Raymond F., Kovari, Ladislau C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734621/
https://ncbi.nlm.nih.gov/pubmed/29779487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1871526518666180521091158
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