Activation of the AMPK-SIRT1 pathway contributes to protective effects of Salvianolic acid A against lipotoxicity in hepatocytes and NAFLD in mice

Background: Salvianolic acid A (Sal A), a natural polyphenol compound extracted from Radix Salvia miltiorrhiza (known as Danshen in China), possesses a variety of potential pharmacological activities. The aim of this study is to determine mechanisms of hepatoprotective effects of Sal A against lipot...

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Publicat a:Front Pharmacol
Autors principals: Li, Songtao, Qian, Qianyu, Ying, Na, Lai, Jianfei, Feng, Luyan, Zheng, Sitong, Jiang, Fusheng, Song, Qing, Chai, Hui, Dou, Xiaobing
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734334/
https://ncbi.nlm.nih.gov/pubmed/33328983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.560905
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