Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome

Monomer tubulin polymerize into microtubules, which are highly dynamic and play a critical role in mitosis. Therefore, microtubule dynamics are an important target for anticancer drugs. The inhibition of tubulin polymerization or depolymerization was previously targeted and exhibited efficacy agains...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Zhong, Cheng, Kayamori, Kensuke, Koide, Shuhei, Shinoda, Daisuke, Oshima, Motohiko, Nakajima‐Takagi, Yaeko, Nagai, Yurie, Mimura, Naoya, Sakaida, Emiko, Yamazaki, Satoshi, Iwano, Satoshi, Miyawaki, Atsushi, Ito, Ryoji, Tohyama, Kaoru, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Lennox, William, Sheedy, Josephine, Weetall, Marla, Iwama, Atsushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734154/
https://ncbi.nlm.nih.gov/pubmed/33037737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14684
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