CDK12 and HER2 coamplification in two urothelial carcinomas with rapid and aggressive clinical progression

Cyclin‐dependent kinase 12 (CDK12), one of the key factors associated with DNA damage response pathways, is located on chromosome 17 proximal to Erb‐B2 receptor tyrosine kinase 2 (ERBB2). In this report, CDK12 and ERBB2 coamplification was detected by targeted next‐generation sequencing in two uroth...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Yanai, Yoshinori, Kosaka, Takeo, Nakamura, Kohei, Aimono, Eriko, Matsumoto, Kazuhiro, Morita, Shinya, Mikami, Shuji, Nishihara, Hiroshi, Oya, Mototsugu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734002/
https://ncbi.nlm.nih.gov/pubmed/33038052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14672
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