CDK12 and HER2 coamplification in two urothelial carcinomas with rapid and aggressive clinical progression

Cyclin‐dependent kinase 12 (CDK12), one of the key factors associated with DNA damage response pathways, is located on chromosome 17 proximal to Erb‐B2 receptor tyrosine kinase 2 (ERBB2). In this report, CDK12 and ERBB2 coamplification was detected by targeted next‐generation sequencing in two uroth...

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Библиографические подробности
Опубликовано в: :Cancer Sci
Главные авторы: Yanai, Yoshinori, Kosaka, Takeo, Nakamura, Kohei, Aimono, Eriko, Matsumoto, Kazuhiro, Morita, Shinya, Mikami, Shuji, Nishihara, Hiroshi, Oya, Mototsugu
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Case Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734002/
https://ncbi.nlm.nih.gov/pubmed/33038052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14672
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