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Mechanistic Model of Signaling Dynamics Across an Epithelial Mesenchymal Transition

Intracellular signaling pathways are at the core of cellular information processing. The states of these pathways and their inputs determine signaling dynamics and drive cell function. Within a cancerous tumor, many combinations of cell states and microenvironments can lead to dramatic variations in...

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發表在:Front Physiol
Main Authors: Wade, James D., Lun, Xiao-Kang, Zivanovic, Nevena, Voit, Eberhard O., Bodenmiller, Bernd
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733964/
https://ncbi.nlm.nih.gov/pubmed/33329028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.579117
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