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Mechanistic regulation of epithelial-to-mesenchymal transition through RAS signaling pathway and therapeutic implications in human cancer

RAS effector signaling instead of being simple, unidirectional and linear cascade, is actually recognized as highly complex and dynamic signaling network. RAF-MEK-ERK cascade, being at the center of complex signaling network, links to multiple scaffold proteins through feed forward and feedback mech...

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Dades bibliogràfiques
Publicat a:J Cell Commun Signal
Autors principals: Tripathi, Kiran, Garg, Minal
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039341/
https://ncbi.nlm.nih.gov/pubmed/29330773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-017-0441-3
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