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Mechanistic regulation of epithelial-to-mesenchymal transition through RAS signaling pathway and therapeutic implications in human cancer

RAS effector signaling instead of being simple, unidirectional and linear cascade, is actually recognized as highly complex and dynamic signaling network. RAF-MEK-ERK cascade, being at the center of complex signaling network, links to multiple scaffold proteins through feed forward and feedback mech...

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Detalhes bibliográficos
Publicado no:J Cell Commun Signal
Main Authors: Tripathi, Kiran, Garg, Minal
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039341/
https://ncbi.nlm.nih.gov/pubmed/29330773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-017-0441-3
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