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Mechanistic regulation of epithelial-to-mesenchymal transition through RAS signaling pathway and therapeutic implications in human cancer

RAS effector signaling instead of being simple, unidirectional and linear cascade, is actually recognized as highly complex and dynamic signaling network. RAF-MEK-ERK cascade, being at the center of complex signaling network, links to multiple scaffold proteins through feed forward and feedback mech...

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Dettagli Bibliografici
Pubblicato in:J Cell Commun Signal
Autori principali: Tripathi, Kiran, Garg, Minal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039341/
https://ncbi.nlm.nih.gov/pubmed/29330773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-017-0441-3
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