Lumican Regulates Ventilation-Induced Epithelial-Mesenchymal Transition Through Extracelluar Signal-Regulated Kinase Pathway

BACKGROUND: Mechanical ventilation used in patients with acute lung injury can damage pulmonary epithelial cells through production of inflammatory cytokines and excess deposition of the extracellular matrix protein lumican. Lumican participates in macrophage inflammatory protein (MIP)-2 and transfo...

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Detalhes bibliográficos
Main Authors: Li, Li-Fu, Chu, Pao-Hsien, Hung, Cheng-Yiu, Kao, Winston W.-Y., Lin, Meng-Chih, Liu, Yung-Yang, Yang, Cheng-Ta
Formato: Artigo
Idioma:Inglês
Publicado em: American College of Chest Physicians 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653345/
https://ncbi.nlm.nih.gov/pubmed/23154825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.12-2058
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