Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway

Mechanical ventilation (MV) used in patients with acute respiratory distress syndrome (ARDS) can increase lung inflammation and pulmonary fibrogenesis. Src is crucial in mediating the transforming growth factor (TGF)‐β1‐induced epithelial–mesenchymal transition (EMT) during the fibroproliferative ph...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Li, Li‐Fu, Kao, Kuo‐Chin, Liu, Yung‐Yang, Lin, Chang‐Wei, Chen, Ning‐Hung, Lee, Chung‐Shu, Wang, Chih‐Wei, Yang, Cheng‐Ta
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661114/
https://ncbi.nlm.nih.gov/pubmed/28598023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13206
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