Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway

Mechanical ventilation (MV) used in patients with acute respiratory distress syndrome (ARDS) can increase lung inflammation and pulmonary fibrogenesis. Src is crucial in mediating the transforming growth factor (TGF)‐β1‐induced epithelial–mesenchymal transition (EMT) during the fibroproliferative ph...

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Bibliografski detalji
Izdano u:J Cell Mol Med
Glavni autori: Li, Li‐Fu, Kao, Kuo‐Chin, Liu, Yung‐Yang, Lin, Chang‐Wei, Chen, Ning‐Hung, Lee, Chung‐Shu, Wang, Chih‐Wei, Yang, Cheng‐Ta
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661114/
https://ncbi.nlm.nih.gov/pubmed/28598023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13206
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