Low-molecular-weight heparin reduces hyperoxia-augmented ventilator-induced lung injury via serine/threonine kinase-protein kinase B

BACKGROUND: High-tidal-volume mechanical ventilation and hyperoxia used in patients with acute lung injury (ALI) can induce the release of cytokines, including high-mobility group box-1 (HMGB1), oxygen radicals, neutrophil infiltration, and the disruption of epithelial and endothelial barriers. Hype...

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Detalhes bibliográficos
Main Authors: Li, Li-Fu, Yang, Cheng-Ta, Huang, Chung-Chi, Liu, Yung-Yang, Kao, Kuo-Chin, Lin, Horng-Chyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136419/
https://ncbi.nlm.nih.gov/pubmed/21726460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-90
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