Lumican Regulates Ventilation-Induced Epithelial-Mesenchymal Transition Through Extracelluar Signal-Regulated Kinase Pathway

BACKGROUND: Mechanical ventilation used in patients with acute lung injury can damage pulmonary epithelial cells through production of inflammatory cytokines and excess deposition of the extracellular matrix protein lumican. Lumican participates in macrophage inflammatory protein (MIP)-2 and transfo...

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Main Authors: Li, Li-Fu, Chu, Pao-Hsien, Hung, Cheng-Yiu, Kao, Winston W.-Y., Lin, Meng-Chih, Liu, Yung-Yang, Yang, Cheng-Ta
格式: Artigo
語言:Inglês
出版: American College of Chest Physicians 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653345/
https://ncbi.nlm.nih.gov/pubmed/23154825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.12-2058
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