The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

Plasmodium parasites rely heavily on glycolysis for ATP production and for precursors for essential anabolic pathways, such as the methylerythritol phosphate (MEP) pathway. Here, we show that mutations in the Plasmodium falciparum glycolytic enzyme, phosphofructokinase (PfPFK9), are associated with...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Fisher, Gillian M., Cobbold, Simon A., Jezewski, Andrew, Carpenter, Emma F., Arnold, Megan, Cowell, Annie N., Tjhin, Erick T., Saliba, Kevin J., Skinner-Adams, Tina S., Lee, Marcus C. S., Odom John, Audrey, Winzeler, Elizabeth A., McConville, Malcolm J., Poulsen, Sally-Ann, Andrews, Katherine T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733947/
https://ncbi.nlm.nih.gov/pubmed/33293381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02842-20
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge