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KRAB zinc finger protein diversification drives mammalian interindividual methylation variability
Most transposable elements (TEs) in the mouse genome are heavily modified by DNA methylation and repressive histone modifications. However, a subset of TEs exhibit variable methylation levels in genetically identical individuals, and this is associated with epigenetically conferred phenotypic differ...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7733849/ https://ncbi.nlm.nih.gov/pubmed/33239447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017053117 |
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