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Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A

Myostatin (MSTN) is a transforming growth factor-β (TGF-β) family member that normally acts to limit muscle growth. The function of MSTN is partially redundant with that of another TGF-β family member, activin A. MSTN and activin A are capable of signaling through a complex of type II and type I rec...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lee, Se-Jin, Lehar, Adam, Liu, Yewei, Ly, Chi Hai, Pham, Quynh-Mai, Michaud, Michael, Rydzik, Renata, Youngstrom, Daniel W., Shen, Michael M., Kaartinen, Vesa, Germain-Lee, Emily L., Rando, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733802/
https://ncbi.nlm.nih.gov/pubmed/33219121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019263117
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