Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight

Among the physiological consequences of extended spaceflight are loss of skeletal muscle and bone mass. One signaling pathway that plays an important role in maintaining muscle and bone homeostasis is that regulated by the secreted signaling proteins, myostatin (MSTN) and activin A. Here, we used bo...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lee, Se-Jin, Lehar, Adam, Meir, Jessica U., Koch, Christina, Morgan, Andrew, Warren, Lara E., Rydzik, Renata, Youngstrom, Daniel W., Chandok, Harshpreet, George, Joshy, Gogain, Joseph, Michaud, Michael, Stoklasek, Thomas A., Liu, Yewei, Germain-Lee, Emily L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519220/
https://ncbi.nlm.nih.gov/pubmed/32900939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014716117
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