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Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type C
Recent studies on developing three-dimensional (3D) brain organoids from stem cells have allowed the generation of in vitro models of neural disease and have enabled the screening of drugs because these organoids mimic the complexity of neural tissue. Niemann-Pick disease, type C (NPC) is a neurodeg...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7733597/ https://ncbi.nlm.nih.gov/pubmed/33311479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03262-7 |
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