PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome

The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27 di-methylation (H3K27me2) and H3K27 tri-methylation (H3K27me3) are marks of facultative heterochromatin which maintains transcriptional repression es...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Meng, Tie-Gang, Zhou, Qian, Ma, Xue-Shan, Liu, Xiao-Yu, Meng, Qing-Ren, Huang, Xian-Ju, Liu, Hong-Lin, Lei, Wen-Long, Zhao, Zheng-Hui, Ouyang, Ying-Chun, Hou, Yi, Schatten, Heide, Ou, Xiang-Hong, Wang, Zhen-Bo, Gao, Shao-Rong, Sun, Qing-Yuan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733509/
https://ncbi.nlm.nih.gov/pubmed/33311485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20242-9
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