PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome

The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27 di-methylation (H3K27me2) and H3K27 tri-methylation (H3K27me3) are marks of facultative heterochromatin which maintains transcriptional repression es...

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Vydáno v:Nat Commun
Hlavní autoři: Meng, Tie-Gang, Zhou, Qian, Ma, Xue-Shan, Liu, Xiao-Yu, Meng, Qing-Ren, Huang, Xian-Ju, Liu, Hong-Lin, Lei, Wen-Long, Zhao, Zheng-Hui, Ouyang, Ying-Chun, Hou, Yi, Schatten, Heide, Ou, Xiang-Hong, Wang, Zhen-Bo, Gao, Shao-Rong, Sun, Qing-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733509/
https://ncbi.nlm.nih.gov/pubmed/33311485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20242-9
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