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Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers

While the majority of cells contain a single nucleus, cell types such as trophoblasts, osteoclasts, and skeletal myofibers require multinucleation. One advantage of multinucleation can be the assignment of distinct functions to different nuclei, but comprehensive interrogation of transcriptional het...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Petrany, Michael J., Swoboda, Casey O., Sun, Chengyi, Chetal, Kashish, Chen, Xiaoting, Weirauch, Matthew T., Salomonis, Nathan, Millay, Douglas P.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733460/
https://ncbi.nlm.nih.gov/pubmed/33311464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20063-w
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