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Resolving single-cell heterogeneity from hundreds of thousands of cells through sequential hybrid clustering and NMF

MOTIVATION: The rapid proliferation of single-cell RNA-sequencing (scRNA-Seq) technologies has spurred the development of diverse computational approaches to detect transcriptionally coherent populations. While the complexity of the algorithms for detecting heterogeneity has increased, most require...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Venkatasubramanian, Meenakshi, Chetal, Kashish, Schnell, Daniel J, Atluri, Gowtham, Salomonis, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320606/
https://ncbi.nlm.nih.gov/pubmed/32207533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa201
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