Myocyte-derived Myomaker expression is required for regenerative fusion but exacerbates membrane instability in dystrophic myofibers

Muscle progenitor cell fusion is required for the formation and regeneration of multinucleated skeletal muscle fibers. Chronic muscle regeneration in Duchenne muscular dystrophy (DMD) is characterized by ongoing fusion of satellite cell (SC) progeny, but the effects of fusion on disease and the mech...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Petrany, Michael J., Song, Taejeong, Sadayappan, Sakthivel, Millay, Douglas P.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253022/
https://ncbi.nlm.nih.gov/pubmed/32310830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136095
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