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Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
Stimulator of interferon genes (STING) is a key regulator of type I interferon and pro-inflammatory responses during infection, cellular stress, and cancer. Here, we reveal a mechanism for how STING balances activation of IRF3- and NF-κB-dependent transcription and discover that acquisition of discr...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7733315/ https://ncbi.nlm.nih.gov/pubmed/31018131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.098 |
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