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CRISPR/Cas9-mediated generation and analysis of N terminus polymorphic models of β(2)AR in isogenic hPSC-derived cardiomyocytes
During normal- and patho-physiological situations, the behavior of the beta2-adrenoreceptor (β(2)AR) is influenced by polymorphic variants. The functional impact of such polymorphisms has been suggested from data derived from genetic association studies, in vitro experiments with primary cells, and...
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| Wydane w: | Mol Ther Methods Clin Dev |
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| Główni autorzy: | , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Gene & Cell Therapy
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7733025/ https://ncbi.nlm.nih.gov/pubmed/33335946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.10.019 |
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