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Age-Dependent Maturation of iPSC-CMs Leads to the Enhanced Compartmentation of β(2)AR-cAMP Signalling

The ability to differentiate induced-pluripotent stem cells into cardiomyocytes (iPSC-CMs) has opened up novel avenues for potential cardiac therapies. However, iPSC-CMs exhibit a range of somewhat immature functional properties. This study explored the development of the beta-adrenergic receptor (β...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Hasan, Alveera, Mohammadi, Neda, Nawaz, Aisha, Kodagoda, Thusharika, Diakonov, Ivan, Harding, Sian E., Gorelik, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601768/
https://ncbi.nlm.nih.gov/pubmed/33053822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102275
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