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Multiscale Simulations Examining Glycan Shield Effects on Drug Binding to Influenza Neuraminidase
Influenza neuraminidase is an important drug target. Glycans are present on neuraminidase and are generally considered to inhibit antibody binding via their glycan shield. In this work, we studied the effect of glycans on the binding kinetics of antiviral drugs to the influenza neuraminidase. We cre...
में बचाया:
| में प्रकाशित: | Biophys J |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The Biophysical Society
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7732775/ https://ncbi.nlm.nih.gov/pubmed/33130120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.10.024 |
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