Characterization of Gene Repression by Designed Transcription Activator-like Effector Dimer Proteins

Gene regulation by control of transcription initiation is a fundamental property of living cells. Much of our understanding of gene repression originated from studies of the Escherichia coli lac operon switch, in which DNA looping plays an essential role. To validate and generalize principles from l...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Becker, Nicole A., Peters, Justin P., Schwab, Tanya L., Phillips, William J., Wallace, Jordan P., Clark, Karl J., Maher, L. James
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732741/
https://ncbi.nlm.nih.gov/pubmed/33091377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.10.007
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