Surprisingly Fast Interface and Elbow Angle Dynamics of Antigen-Binding Fragments

Fab consist of a heavy and light chain and can be subdivided into a variable (V(H) and V(L)) and a constant region (C(H)1 and C(L)). The variable region contains the complementarity-determining region (CDR), which is formed by six hypervariable loops, shaping the antigen binding site, the paratope....

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Fernández-Quintero, Monica L., Kroell, Katharina B., Heiss, Martin C., Loeffler, Johannes R., Quoika, Patrick K., Waibl, Franz, Bujotzek, Alexander, Moessner, Ekkehard, Georges, Guy, Liedl, Klaus R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732698/
https://ncbi.nlm.nih.gov/pubmed/33330636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.609088
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