Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics

Sharks and other cartilaginous fish are the phylogenetically oldest living organisms that have antibodies as part of their adaptive immune system. As part of their humoral adaptive immune response, they produce an immunoglobulin, the so-called immunoglobulin new antigen receptor (IgNAR), a heavy-cha...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Front Mol Biosci
Asıl Yazarlar: Fernández-Quintero, Monica L., Seidler, Clarissa A., Quoika, Patrick K., Liedl, Klaus R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Molecular Biosciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093575/
https://ncbi.nlm.nih.gov/pubmed/33959632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.639166
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