Vitamin D/CD46 Crosstalk in Human T Cells in Multiple Sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), in which T-cell migration into the CNS is key for pathogenesis. Patients with MS exhibit impaired regulatory T cell populations, and both Foxp3+ Tregs and type I regulatory T cells (Tr1) are dysfunctional....

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Killick, Justin, Hay, Joanne, Morandi, Elena, Vermeren, Sonja, Kari, Saniya, Angles, Thibault, Williams, Anna, Damoiseaux, Jan, Astier, Anne L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732696/
https://ncbi.nlm.nih.gov/pubmed/33329593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.598727
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