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Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis
Loss of Treg function appears to be a critical factor in the pathogenesis of human autoimmune diseases. Attention has focused on defects of CD4(+)CD25(high) Tregs, and techniques have been developed to determine their function. In contrast, the role of Tr1 regulatory T cells, which secrete the antii...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635165/ https://ncbi.nlm.nih.gov/pubmed/17099776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29251 |
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