The Calcilytic Drug Calhex-231 Ameliorates Vascular Hyporesponsiveness in Traumatic Hemorrhagic Shock by Inhibiting Oxidative Stress and miR-208a-Mediated Mitochondrial Fission

BACKGROUND: The calcium-sensing receptor (CaSR) plays a fundamental role in extracellular calcium homeostasis in humans. Surprisingly, CaSR is also expressed in nonhomeostatic tissues and is involved in regulating diverse cellular functions. The objective of this study was to determine if Calhex-231...

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Bibliographische Detailangaben
Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Lei, Yan, Peng, Xiaoyong, Hu, Yi, Xue, Mingying, Li, Tao, Liu, Liangming, Yang, Guangming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732383/
https://ncbi.nlm.nih.gov/pubmed/33343806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4132785
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