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Calhex231 ameliorates myocardial fibrosis post myocardial infarction in rats through the autophagy‐NLRP3 inflammasome pathway in macrophages

The calcium‐sensing receptor (CaSR) is involved in the pathophysiology of many cardiovascular diseases, including myocardial infarction (MI) and hypertension. The role of Calhex231, a specific inhibitor of CaSR, in myocardial fibrosis following MI is still unclear. Using Wistar rats, we investigated...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Liu, Wenxiu, Sun, Jiaxing, Guo, Yutong, Liu, Na, Ding, Xue, Zhang, Xin, Chi, Jinyu, Kang, Ningning, Liu, Yue, Yin, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701583/
https://ncbi.nlm.nih.gov/pubmed/33043596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15969
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