Calhex231 ameliorates myocardial fibrosis post myocardial infarction in rats through the autophagy‐NLRP3 inflammasome pathway in macrophages

The calcium‐sensing receptor (CaSR) is involved in the pathophysiology of many cardiovascular diseases, including myocardial infarction (MI) and hypertension. The role of Calhex231, a specific inhibitor of CaSR, in myocardial fibrosis following MI is still unclear. Using Wistar rats, we investigated...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Liu, Wenxiu, Sun, Jiaxing, Guo, Yutong, Liu, Na, Ding, Xue, Zhang, Xin, Chi, Jinyu, Kang, Ningning, Liu, Yue, Yin, Xinhua
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701583/
https://ncbi.nlm.nih.gov/pubmed/33043596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15969
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