Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer

Splicing dysregulation, which leads to apoptosis resistance, has been recognized as a major hallmark for tumorigenesis and cancer progression. Targeting alternative splicing by either increasing pro-apoptotic proteins or inhibiting anti-apoptotic proteins in tumor cells may be an effective approach...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Li, Yonghong, Gao, Xiaoling, Wei, Chaojun, Guo, Rui, Xu, Hui, Bai, Zhongtian, Zhou, Jianye, Zhu, Jun, Wang, Wanxia, Wu, Yu, Li, Jingzhe, Zhang, Zhongliang, Xie, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732305/
https://ncbi.nlm.nih.gov/pubmed/33052877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103766
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